ngs
Surveillance NGS Infrastructure
Genomic Surveillance at Scale: Lessons from the COVID-19 Response
What building global pathogen surveillance infrastructure during SARS-CoV-2 taught me about reproducible pipelines, data federation, and scientific communication under pressure.
· 10 min
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CRISPR Genomics AMR
Thinking About CRISPR Off-Target Risk in a Clinical Context
How to frame off-target assessment for gene therapy applications — frequency, location, functional consequence, and the questions regulators actually ask.
· 8 min
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Nextflow NGS Infrastructure
Nextflow DSL2 Patterns I Actually Use
Practical patterns for scalable NGS pipelines in Nextflow DSL2 — module composition, subworkflows, and config layering for multi-environment deployments.
· 9 min
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NGS INDUCE-seq Genomics
INDUCE-seq: A PCR-Free Window into the Genome's Break Landscape
An overview of INDUCE-seq, how it avoids amplification bias, and why PCR-free DSB detection changes what we can see in the breakome.
· 7 min
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